Nurami Medical’s ArtiFascia® for dural repair is a porous nanofiber, soft tissue regeneration graft made of medical grade synthetic polymers. The multilayer graft incorporates a novel, temperature-sensitive and visco-elastic sealant, and boasts biodegradable and bioabsorbable functionality. Current dura patches suffer from significant limitations, such as dangerous CSF leaks, which occur in 15% of procedures, risk of disease transmission, adhesions to the brain, cumbersome handling and suturing, poor mechanical properties, and the cost of using both a graft and sealant.
The porous nanofiber patch mimics natural extracellular matrices, providing a scaffold, which enables infiltration of fibroblasts and cells from the intact tissue, enhancing tissue regeneration, ultimately replacing damaged dural tissue
The temperature-sensitive and visco-elastic sealant becomes a deformable gel that penetrates suture holes and conforms to fibers, even when stretched. This novel gel eliminates the need for surgical sealants, ensuring watertight sealing of the site, reducing CSF leakage, and potentially life-threatening pathogen entry.
In-vivo testing of ArtiFascia® has validated its supremacy over the state of the art, in terms of preventing leakage, mechanical strength, regeneration capabilities, tissue integration, suture retention and more.